New study by ramazzini institute confirms aspartame. Efsa assesses new aspartame study and reconfirms its safety the afc panel of the european food safety authority efsa has evaluated the new longterm study on the carcinogenicity of aspartame conducted by the european ramazzini foundation in bologna, italy. The history of aspartame dates back to 1965 when the lowcalorie sweetener was accidentally discovered by chemist james schlatter. The carcinogenicity studies of the ramazzini institute on apm shown. The molecule breaks down to diketopiperazine, a tumor agent. The institute tied to pd investigated by the american congress. Aspartame, updated assessment of risks on health, cancer and pregnancy context aspartame is one of the most widely used artificial sweetener, is it safe. The most recent official attempt to settle the controversy was provided by the european food safety authoritys or efsa panel on food additives and nutrient sources added to food or ans in december 20.
A novel innovative device for qualitative estimation of glucose, protein. Aspartame is currently used in a variety of food and beverage items, such as yogurt, desserts and carbonated drinks. Ramazzini study on radiofrequency cell phone radiation. Il gruppo di esperti ha valutato gran parte dei dati emersi dal nuovo studio sull aspartame forniti allefsa dalla fondazione europea ramazzini. Efsa has reported that the results of the ramazzini institute studies do not change its conclusions regarding the noncarcinogenicity of aspartame efsa, 2009, 20.
Aspartame induces lymphomas and leukaemias in rats. Jun 24, 2006 scientific director of the european ramazzini foundation and primary author of the aspartame study, dr. The studies in which tumor responses were reported were all conducted by the european ramazzini foundation on oncology and. Lack of potential carcinogenicity for aspartame systematic. In 2007 the european ramazzini foundation in bologna, italy, published findings of a new study on the carcinogenicity of aspartame in rats. These data demonstrated for the first time that aspartame is a carcinogenic agent, inducing various types of malignant tumors in rats, even at dose levels currently considered acceptable for humans. Ramazzini institutes second study confirms aspartame. European food standards agency efsa blesses aspartame. The european ramazzini foundation erf animal cancer studies on aspartame. European food safety authority efsa, 20, the results of the studies performed by soffritti et al. Erf stands behind aspartame study results, announces ongoing research on artificial sweeteners.
Aspartame, updated assessment of risks on health, cancer and. Worlds largest animal study on cell tower radiation confirms cancer link scientists call on the world health organization international agency for research on cancer to reevaluate the carcinogenicity of cell phone radiation after the ramazzini institute and us government studies report finding the same unusual cancers. The european food safety authority efsa commenced a reevaluation of aspartame as part of the systematic reevaluation of all food additives authorised in the eu prior to 20 january 2009. Efsa confirms safety of sucralose, rejecting findings of. The first ramazzini study on aspartame, published in 2005, used 1800 rats. Before the study even began, it was revealed that efsa had hired scientists linked to the food industry to perform the research. First experimental demonstration of the multipotential. The efsa panel requested information from the authors of the ramazzini studies to assist in its evaluation. European food safety authority efsa to assess the erf aspartame carcinogenicity study. Aspartame is a sweetener authorised as a food additive in the eu. This is my work, i am the author and i own the to the work. Apm was administered with feed to 8weekold spraguedawley rats 100150sexgroup, at concentrations of 100,000, 50,000, 10,000, 2,000, 400, 80, or 0 ppm. A second study conducted by the european ramazzini foundation erf confirms the carcinogenicity of aspartame. There are three epidemiologic studies that were published after 2009.
Aspartame study regarding ramazzini study, which looked at long term exposure to aspartame through feed in mice, efsa identified several flaws in its design. So when they released the studies showing aspartame to be a multipotential carcinogen industry fought to convince the public not to accept them by saying the rats had respiratory disease. In previous evaluations by jecfa and the scf, an adi of 40 mgkg bwday was established based on chronic toxicity in animals. Aspartame induces lymphomas and leukaemias in rats soffritti et al. The aspartame industry really fears the ramazzini institute because they are world renowned for cancer research. Results of study on the carcinogenicity of the artificial. The efsa panel on food additives and nutrient sources added to food ans considered for its assessment the publication from soffritti et al. Herman koeter who was head of the committee resigned and said. Results of study on the carcinogenicity of the artificial sweetener aspartame. Given the shortcomings of efsas risk assessment of aspartame, and the. A questo punto report introduce il parere dellistituto di ricerche oncologiche ramazzini, secondo il quale le dosi calcolate dallefsa vanno. The report was issued by the efsa panel on food additives and nutrient sources added to food ans, and basically said that the data supplied by the ramazzini foundation in a paper by soffritti.
More than 10 years ago, the ramazzini institute signed a research according to which aspartame would be carcinogenic. Scientists at the ramazzini foundation found that when administered to rats for their entire life span, aspartame, an artificial sweetener used in more than 6,000 food and pharmaceutical products, induces an increase in lymphomas and. Jun, 2011 the commission pressed efsa to carry out a fresh risk assessment of the sweetener immediately in the wake of growing concern among meps and others about its effect on. Dubious efsa announcement of aspartame safety saturates. In a previous study conducted at the cesare maltoni cancer research center of the european ramazzini foundation cmcrcerf, we demonstrated for the first time that aspartame apm is a multipotent carcinogenic agent when various doses are administered with feed to spraguedawley rats from 8 weeks of age throughout the life span. Overall findings continue to support lack of carcinogenicity from aspartame consumption. The new ramazzini study, like the first, allows rats to live out their natural life rather than.
Although efsa found many problems with the ramazzini study, the panel stated that one of the reasons for the confounding conclusions by ramazzini may be due, in part, to the fact that the rats. Fresh fears raised about aspartame society the guardian. Initially, the ramazzini authors chose not to fulfill efsa s data request. Likewise, in 2007, the fda concluded, it finds no reason to alter its previous conclusion that aspartame is safe as a general purpose sweetener in food u. Efsa noted numerous issues with the ramazzini institute study on sucralose, including. In may 2011, efsa was asked by the european commission to bring forward the full reevaluation of the safety of aspartame e 951, which was previously. Living in a chemical world, to be held in bologna, italy from september 1821, 2005. Food and drug administration approved aspartame for use in certain foods in 1981, soft drinks in 1993, and authorized aspartame as a generalpurpose sweetener for foods and beverages in 1996. So, the ramazzini studies confirmed aspartame as a multipotential carcinogen. In its opinion, the panel concluded, on the basis of all the evidence currently available, that there is no need.
Amongst food additives, aspartame is one of the most controversial, especially in the usa, but also in the uk and the eu. Nov 17, 2005 the cesare maltoni cancer research center of the european ramazzini foundation has conducted a longterm bioassay on aspartame apm, a widely used artificial sweetener. Risk communication, media amplification and the aspartame. In europe, it is authorised to be used as a food additive in foodstuffs such as drinks, desserts, sweets, dairy, chewing gums, energyreducing and weight control products and as a tabletop sweetener. Aspartame and its breakdown products have been the subject.
The european food safety authoritys efsa s ans panel adopted an opinion on this study in january 2009. Sep 23, 2008 on 14 july 2005, the ramazzini foundation held a press conference on the cancer risks posed by the sweetener aspartame, which received worldwide media attention. Overwhelming scientific evidence confirms aspartame safety. The ramazzini foundation however is refusing to close the book on aspartame. This is a faithful summary of the leading report produced in 20 by the european food safety authority efsa. The european food safety authority efsa has been asked by the european commission to assess the carcinogenicity study performed by the european ramazzini foundation of oncology and environmental sciences erf on the artificial sweetener aspartame, which was reported in publications in 2005 and 2006.
Efsa confirms safety of sucralose, rejecting findings of ramazzini institute. It is a white, odourless powder, approximately 200 times sweeter than sugar. The artificial sweetener aspartame has been the subject of several controversies since its initial. In particular the scientists said the length of the study meant that erroneous conclusions could be drawn. Dec 19, 2005 the european food safety authority efsa has received the primary data for ramazzini foudations recent study on the sweetener aspartame and is commencing its risk assessment as a matter of priority. European food safety authority reconfirms safety of aspartame.
The panel also said there was no risk to the developing foetus from aspartame consumption, and that aspartame does not harm the brain, nervous system or cognitive function in. In its opinion, the panel concluded, on the basis of all the evidence. In efsa s 20 scientific opinion of the safety of aspartame, the authority concluded that aspartame and its breakdown products pose no toxicity concern for consumers at current levels of exposure. Efsa has rejected their aspartame studes twice here and here and the epa wont use them either. This statement further confirms efsas 2006 statement regarding an earlier ramazzini study, which alleged that aspartame consumption may cause cancer. One promising example of such novel methods is known as syrcle. After the evaluation of data from required studies, the u. The efsa ans panel provides a scientific opinion on the safety of aspartame e 951. In an article published in the march 2006 issue of environmental health perspectives ehp soffritti et al.
Mission possible world health international 9270 river club parkway duluth, georgia 30097 telephone. Ramazzini set to publish new pathology slides aspartame study. European food safety authority slams ramazzini study, finds. Quali sono i lavori recenti svolti dallefsa sullaspartame e quali studi ha preso. Efsa was aware of the upcoming study of the ramazzini foundation on aspartame and had requested detailed information from them. The ramazzini institute used a lifetime model of their own design that has been. The afc panel of the european food safety authority efsa has evaluated the new longterm study on the carcinogenicity of aspartame conducted by the ramazzini institute. Lifespan exposure to low doses of aspartame beginning during. In contrast, studies conducted in the 1970s by, or under.
This is also a continuation of my official submission to the efsa call for data on aspartame on the 7th of july, 2011. Efsa acknowledged improvements in design of the scientific study. Scientific opinion on the reevaluation of aspartame e 951 as a food. The problem is that when efsa asks them erf to elaborate on. Morando soffritti of the european ramazzini foundation will present the results of a new study confirming the carcinogenicity of aspartame on april 23, 2007 at the mount sinai medical school of new york, where he also will receive the prestigious irving j. It is based on this rationale that the european ramazzini foundation performed a megaexperiment on 1,800 rats and demonstrated that, in our experimental conditions, aspartame is a multipotential carcinogenic agent soffritti et al. Herman koeter, efsa acting executive director, efsa considers that the results of this new study on aspartame by ramazzini researchers do not provide. Its director, dr morando soffritti, told journalists at the rome conference that it stands by its research finding that. Scientific opinion on the reevaluation of aspartame e 951. European food safety authority slams ramazzini study. The european food safety authority efsa commenced a reevaluation of aspartame as part of the systematic.
Aspartame is an intense, lowcalorie, artificial sweetener. The results of this study will be presented april 23, 2007 at the mount sinai medical school of new york, where erf scientific director morando soffritti will receive the third irving j. In april 2017, the european food safety authoritys efsa scientific panel on food additives and nutrient sources added to food ans discussed the 2016 publication by soffritti et al. Food safety authority says aspartame not linked to cancer. The european food safety authority efsa said it considers carefully any new evidence that was not available at the time an opinion is adopted. Efsa completes full risk assessment on aspartame and.
Aspartame induces lymphomas and leukaemias in rats request pdf. European food safety authority confirms sucralose is safe and does. I explicitly give efsa permission to exchange the book chapter i attach to this email with the joint faowho expert committee on food additives. May 15, 2006 the ramazzini foundation however is refusing to close the book on aspartame. Publication will reignite the aspartame debate after the european food safety authority efsa dismissed the first ramazzini rat study, saying there was no dose response in the experiment and that the rats were sick with pulmonary infections. Apr 17, 2007 new study by ramazzini institute confirms aspartame carcinogenic.
In efsas 20 scientific opinion of the safety of aspartame, the authority concluded that aspartame and its breakdown products pose no toxicity concern for consumers at current levels of exposure. Industry did everything they could to get the european food safety authority, efsa, not to accept them. Adding it does not consider it appropriate to suggest any change in consumers diets relative to aspartame on the basis of the information it currently has. Dopo aver valutato i risultati del nuovo studio sullaspartame. Moreover, the ramazzini institute was doubted of not having used international standards. Efsa assesses new aspartame study and reconfirms its safety. In 2005, the european ramazzini foundation published important experimental data demonstrating the carcinogenicity of aspartame. She said the ramazzini institute had released several studies over the past few years and efsa had an obligation to look at them. Jan 08, 20 the european food safety authority efsa has today launched a public consultation on its draft scientific opinion on the safety of the artificial sweetener aspartame. Aspartame should receive the lowest possible priority for. The current adi for aspartame is deemed to be safe for the general population. The study is currently being published in the european journal of oncology and final results will be presented at the 3rd international scientific conference of the collegium ramazzini, framing the future in light of the past. In may 2011, the european food safety authority efsa accepted a request from the european commission for the reevaluation of the safety of aspartame in 2012.
Dec 10, 20 aspartame and its breakdown products are safe for human consumption at current levels of exposure, efsa concludes in its first full risk assessment of this sweetener. The same european food safety authority intervened. The cesare maltoni cancer research center of the european ramazzini foundation of oncology and. Jan 17, 2017 this statement further confirms efsas 2006 statement regarding an earlier ramazzini study, which alleged that aspartame consumption may cause cancer. New results on glyphosate danger from the ramazzini. Scientific director of the european ramazzini foundation and primary author of the aspartame study, dr.
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